$1.6M awarded to University of Colorado innovators to advance their discoveries
Twelve University of Colorado research teams competed for a combined $1.6 million in startup funding grants in this year鈥檚 Lab Venture Challenge (LVC). Judges from CU's entrepreneurial network heard Shark Tank-style pitches across two nights at the Dairy Arts Center in Boulder, one for innovations in biosciences and another for physical sciences and engineering.
Through LVC, top innovators from 麻豆免费版下载Boulder, Denver and Colorado Springs can compete for grants to fund projects that address a commercial need, have a clear path to a compelling market and have strong scientific support. The , with matching funds from Venture Partners at 麻豆免费版下载Boulder.
This culminating event for these groundbreaking teams showcased the university鈥檚 initiative to support innovators from discovery to economic success. Venture Partners at 麻豆免费版下载Boulder runs LVC, the university鈥檚 commercialization arm and central resource for researchers who want to translate their work into impactful business and social ventures. As part of the LVC program, all the competitors worked with Venture Partners to protect their innovations and practice their funding pitches for business audiences. LVC awardees will continue to work and collaborate with Venture Partners on their path to commercialization.
"At this early stage, funding is essential, but can be a challenge to obtain," said Joshua Bennett, director of LVC and assistant director of licensing at Venture Partners. "All of these teams have promising innovations ready to launch new businesses. LVC is a unique opportunity for those innovators to receive that vital funding, and we鈥檙e proud to work with the State of Colorado to make it happen."
Remarkable science to the stage
One biosciences winning team is growing stem cells for blood cancer treatment in microgravity, where cells float freely instead of being stirred by machines, with the goal of producing enough umbilical cord blood cells to treat adult patients. Another found that removing a single protein from the immune cells that shield triple-negative breast cancer shrank tumors in mice and drew cancer-killing T cells into them.听
On the physical sciences side, Ptarmigan Clockworks is turning optical clocks, among the most precise timekeepers ever built, from one-of-a-kind lab instruments into devices that can be manufactured at scale. Fortifyd鈥檚 3D-printed helmet liners withstood up to 10 times more impact than conventional foams of the same density in peer-reviewed research. Other teams are building a stretchy liquid-metal 鈥渆lectronic skin鈥� that maps pressure inside prosthetic sockets to catch painful fit problems early, a chip-scale atomic clock that transforms light energy into sound waves, and an MRI technique that spots cartilage breakdown years before it shows up on standard scans.
From research to real-world impact
To date, LVC has funded over 155 projects through more than 81 new deep-tech startup companies; collectively, these companies have raised over $691 million in follow-on financing.
Two past LVC winners returned to the showcases to share progress updates.听
, a 2025 biosciences winner, is developing obesity treatments inspired by an appetite-suppressing compound the team discovered in python blood, and has since closed a $750,000 pre-seed funding round.听
Mesa Quantum, a 2023 physical sciences winner led by CEO Sristy Agrawal, builds chip-scale atomic clocks and quantum sensors that provide precise timing and navigation when GPS is jammed or unavailable. The company has raised nearly $16 million in venture funding as it moves toward volume manufacturing.
Early support from LVC can carry a lab discovery a long way. This year, Forge Nano announced plans to go public, making it 麻豆免费版下载Boulder鈥檚 11th "unicorn," meaning a startup valued at $1 billion or more while still privately held. Its atomic-scale coating technology, now used in batteries and AI-era chipmaking, traces back to ALD NanoSolutions, a 麻豆免费版下载Boulder spinout that received early funding through the 麻豆免费版下载and OEDIT partnership that later became LVC.听
As this year鈥檚 teams take their innovations from the lab toward the market, the next Forge Nano may already be among them.
This year鈥檚 LVC was additionally made possible by , , , , , , and
Photo Credits: Monico Candelaria
2026 Physical Sciences Winners

Winning Teams L-R: Fortifyd (PI: Robert MacCurdy, Presenter: Teri Ham), Orva Energy (PI: Chunmei Ban, Presenter: Evan Flitz), Ptarmigan Clockworks (Presenter/PI: Benjamin Hunt); RheoSynapse (Presenter/PI: 听Jianliang Xiao); Choyu Networks (Presenter/PI: Elliot Eichen); and Sonoptic (PI: Matt Eichenfield, Presenter: Daniel Lesko)
$200,000 鈥� Tunable 3D-Printed Helmet Liners for Multi-Impact Protection
Today鈥檚 helmets are still largely designed around single-impact foam, even as athletes face a mix of severe collisions, repeated smaller hits and rotational forces. Fortifyd is reimagining helmet protection with a plate-lattice structure that manages the full impact spectrum in one system. Peer-reviewed research showed up to 10x higher impact tolerance than conventional foams at equal density. The team has formed a startup, , to bring their innovation to market.
- , Embark Deep Tech Startup Creator and BS Alum of Business at 麻豆免费版下载Boulder, Co-Founder and CEO of Fortifyd, hamteri@gmail.com听
- , Associate Professor of Mechanical Engineering at 麻豆免费版下载Boulder, PI, Technical Advisor
- , Master of Science Alum and PhD Student of Computer Science at 麻豆免费版下载Boulder, Lead Software Engineer at Fortifyd
- , Graduate Student of Mechanical Engineering at 麻豆免费版下载Boulder, Lead Product Engineer at Fortifyd
- , Product Strategy and Commercialization Leader at Fortifyd
Read More About the Science
- (2024, Advanced Materials Technologies)
- (2024, Additive Manufacturing)
- (2024, Advanced Materials)
$170,000 鈥� AI-Accelerated Advanced Battery Materials
Developing a new class of high-energy, beyond-lithium battery active materials made entirely from earth-abundant, domestically sourced elements. By integrating ML/AI with proprietary advanced crystal-structure engineering, their materials enable energy parity with conventional lithium systems at a fraction of the cost. The team has formed a startup, , to bring their innovation to market.
- , PhD Candidate of Chemical and Biological Engineering at 麻豆免费版下载Boulder, Co-Founder and Principal Materials Engineer of Orva Energy, evan@orvaenergy.com听
- , Professor of Mechanical Engineering at 麻豆免费版下载Boulder, PI, Co-Founder and Chief Scientific Advisor of Orva Energy
- , PhD Alum of Chemical Engineering at 麻豆免费版下载Boulder, Scientific Advisor at Orva Energy听
In the News
- (2026, National Laboratory of the Rockies)
$140,000 鈥� An Autonomous Optical Clock
Ptarmigan is developing the autonomous optical clock, the first clock to eliminate the environmental and calibration constraints that have kept optical clocks bespoke devices. For the first time, optical precision can be manufactured at scale and deployed as network infrastructure for distributed sensing, quantum systems and national security. The team has formed a startup, , to bring their innovation to market.
- , and Graduate Student of Physics at 麻豆免费版下载Boulder, PI, Co-Founder and CEO of Ptarmigan Clockworks, benjamin.hunt@ptarmigan-clockworks.com听
- , Commercialization for Ptarmigan Clockworks听
- Andrew Ludlow, , Scientific Advisor
- , Professor Adjoint of Physics at 麻豆免费版下载Boulder and Fellow at JILA, Scientific Advisor
$100,000 鈥� Practical Post-Quantum Cryptography for Resource-Constrained Networks and Devices
New quantum-resistant algorithms have been developed that prevent quantum computers from breaking the public-key algorithms that secure almost all internet communications. This technology works where these new public-key algorithms do not: low-power IoT devices and limited-bandwidth networks. The team has formed a startup, , to bring their innovation to market.
- , Research Associate of Computer Science at 麻豆免费版下载Boulder, PI, Co-Founder and CTO of Choyu Networks, elliot.eichen@colorado.edu听
- , Co-Founder and CBO of Choyu Networks
- , Co-Founder and Investment Advisor of Choyu Networks
- , PhD Candidate in Electrical, Computer and Energy Engineering at 麻豆免费版下载Boulder, Cryptography SME
- , Marketing for Choyu Networks
- , Assistant Professor of Computer Science at 麻豆免费版下载Boulder, Advisor
- , Associate Professor of Computer Science at 麻豆免费版下载Boulder, Advisor
$100,000 鈥� Intelligent Electronic Skin Transforming Prosthetic Diagnostics
Intelligent liquid-metal electronic skin embedded in prosthetic sockets for real-time pressure mapping. AI-driven analytics learn each patient鈥檚 pressure patterns to predict socket issues before they cause pain. This affordable, scalable system gives prosthetists data-driven insights to improve socket fit and daily comfort. The team has formed a startup, RheoSynapse Inc., to bring their innovation to market.
- Jianliang Xiao, Associate Professor of Mechanical Engineering at 麻豆免费版下载Boulder, PI, Co-Founder of RheoSynapse, jianliang.xiao@colorado.edu听
- Dhileep Kumar Jayashankar, PhD Candidate in Mechanical Engineering at 麻豆免费版下载Boulder, Lead Researcher听
- Ruili Zhang, Graduate Student of Mechanical Engineering at 麻豆免费版下载Boulder
Read More About the Science
- (2021, Research)
- (2023, npj Flexible Electronics)
$100,000 鈥� Optical Timekeeping Made Portable: The Single-Chip Acoustic-Optoelectronic Oscillator
A chip-scale microwave oscillator that generates exceptionally pure signal tones by circulating energy between sound and light on a single chip. By amplifying the sound waves directly on-chip 鈥� with no electronics in the loop 鈥� the device targets the signal purity of room-sized precision oscillators in a package small enough for portable radar, navigation and communications.
- , Research Scientist in Electrical, Computer and Energy Engineering at 麻豆免费版下载Boulder, Engineer听
- , Endowed Chair in Quantum Engineering at 麻豆免费版下载Boulder, PI, 听matt.eichenfield@colorado.edu听
- , Professor of Electrical, Computer and Energy Engineering at 麻豆免费版下载Boulder, Scientific Advisor
- , PhD Student of Electrical, Computer and Energy Engineering at 麻豆免费版下载Boulder, Engineer
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2026 Biosciences Winners

Winning Teams L-R (back row first): Potentis Imaging (PI: Corey Neu, Presenter: Yassmeen Youssef); Anesa Bio (Presenter/PI: Michael Stowell); Opera Space (PI: Tobias Niederweiser, Presenter: Stuart Tozer); Regelife (PI: Kristi Anseth, Presenter: Mark Ma); Enlixa Bio (PI: Dylan Taatjes, Presenter: Nik Chopra); Sieyax (Presenter/PI: Xiang Wang)
$200,000 鈥� Long-Acting, Non-Opioid Therapy for Chronic Pain
A long-acting non-opioid analgesic that selectively targets CaV3.2 to provide sustained relief from chronic pain without abuse liability. The team has formed a startup, , to bring their innovation to market.
- Michael Stowell, Professor of Molecular, Cellular and Developmental Biology at 麻豆免费版下载Boulder, PI, Co-Founder and CSO of AnesaBio, michael.stowell@colorado.edu听
- Slobodan Todorovic, , Co-Founder and CMO of AnesaBio
- , Advisor
- Joe Lyssikatos, Advisor
Read More About the Science
- (2025, bioRxiv)
$170,000 鈥� Novel Electromechanics Biomarkers for Cartilage Health Diagnostics
A noninvasive MRI technique that reveals cartilage's hidden electrical and mechanical signatures under joint loading, detecting early degeneration years before it appears on standard scans. This new biomarker could help diagnose osteoarthritis risk sooner and track whether emerging joint-preserving therapies are actually working. The team has formed a startup, Potentis Imaging, to bring their innovation to market.
- Corey Neu, Professor of Mechanical Engineering at 麻豆免费版下载Boulder, PI, Co-Founder of Potentis Imaging, cpneu@colorado.edu听
- Yassmeen Youssef, Co-Founder of Potentis Imaging
$140,000 鈥� EYA Degraders: Releasing the Immune Brake in Triple-Negative Breast Cancer
Triple-negative breast cancer resists immunotherapy because tumor-associated macrophages are reprogrammed to shield it. The team discovered that eliminating a single protein, EYA3, from those macrophages shrinks tumors in mice and draws cancer-killing T cells inward. They are now building bifunctional molecules that destroy EYA3 outright, making immunologically cold tumors treatable. The team has formed a startup, , to bring their innovation to market.
- Xiang Wang,Associate Professor of Chemistry at 麻豆免费版下载Boulder, PI, Co-Founder and Co-CSO of Sieyax, xiang.wang@colorado.edu听
- Heide Ford, , Co-Founder and Co-CSO of Sieyax
- Rui Zhao, , Co-Founder and Co-CSO of Sieyax
- Ginny Orndorff, Co-Founder and CEO of Sieyax
Read More About the Science
- (2024, ChemMedChem)
- (2026, bioRxiv)
$100,000 鈥� AI Designed Biomaterials for Regenerative Medicine
Cell therapies are grown in Matrigel, an undefined mouse tumor extract that varies lot to lot; every alternative is one formulation sold for every use. Regelife uses machine learning to design the matrix around the cell, turning 18 months of trial and error into one kit. In ALS, the matrix decides whether transplanted neurons survive. Built on Anseth Lab hydrogel chemistry at 麻豆免费版下载Boulder. The team has formed a startup, , to bring their innovation to market.
- , Distinguished Professor of Chemical and Biological Engineering, PI, Co-Founder and CSO of Regelife
- , Co-Founder and CEO of Regelife, mark@regelife.bio听
- Hideyuki Okano, Scientific Co-Founder of Regelife
- Max Yavitt
$100,000 鈥� A Real-Time Screening Platform for Drugs Targeting Transcription Regulators
RIFT (Real-time In vitro Fluorescent Transcription), developed in the Taatjes Lab at 麻豆免费版下载Boulder, enables direct visualization of individual drug-target interactions in real time, distinguishing on-target from off-target activity to improve drug screening ahead of clinical trials. The team has formed a startup, , to bring their innovation to market.
- , Embark Startup Founder, Co-Founder and CEO of Enlixa Bio, nik@enlixabio.com听
- , Professor of Biochemistry at 麻豆免费版下载Boulder, PI, Founding Scientist of Enlixa Bio
Read More About the Science
- (2025, Cell Reports)
$100,000 鈥� Zero-G Cancer Treatments
A microgravity biomanufacturing platform designed to expand umbilical cord blood stem cells for treating blood cancers. By keeping cells naturally suspended without mechanical agitation, the technology aims to preserve their therapeutic advantages while producing enough cells to treat adult patients, unlocking the potential of cord blood transplantation. The team has formed a startup, Opera Space LLC, to bring their innovation to market.
- , Associate Director of BioServe Space Technologies at 麻豆免费版下载Boulder, Co-Founder of Opera Space LLC, stuart.tozer@colorado.edu听
- , Assistant Research Professor of Bioastronautics, PI, Co-Founder of Opera Space LLC
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