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Research Interests

Flow physics, physiological and biomedical flows,Ìýcardiovascular and cerebrovascular phenomena,Ìýcomputational fluid and solid mechanics,Ìýquantitative image processing

Assistant Professor Debanjan Mukherjee's inter-disciplinary research group is broadly interested in unraveling the fundamental behavior of complex flow and transport phenomena. Specifically, his research program focuses on understanding the flow, transport, and mechanical underpinnings of physiological processesÌýand on leveraging this understanding to develop tools for disease biomechanics, medical device design, treatment planning, and drug delivery. A primary application area is in cardiovascularÌýand cerebrovascular processes in healthy and diseased states, where theÌýgroup conducts targeted investigations on diseases like stroke, thrombosis, and embolisms. The tools and technologies developed also have applications broadly in other physiological and disease phenomena. Finally, at a more fundamental level, theyÌýare interested in various theoretical and numerical aspects of flow physics, particularly involving particle-based and particle-laden flows, with cross-cutting applications in biomedical and advanced manufacturing systems.

Societal Impact

Flow physics and mechanical forces play a key underlying role in a variety of diseases. Our research aims to establish an improved understanding of this connection. This not only provides deeper insights into the disease itself, but also enables significant improvements in treatment and patient care. This is particularly impactful when we consider cardiovascular diseases like heart attack and stroke, which constitute the leading cause of death and disability worldwide, affecting millions of individuals and their families every year. Key improvements in treatment planning, and design and deployment of medical devices, can substantially affect patient health and treatment outcomes – an aspect that comprises the core motivation of our research. In addition to these contributions, as a group, we are passionate about educating future engineers from a diverse set of backgrounds to tackle challenging problems requiring multi-disciplinary approaches.

Select Publications

• Teeraratkul, C., Krishnamurthy, A., and Mukherjee, D. Computational Modeling Of Immersed Non-spherical Bodies In Viscous Flows To Study Embolus-Hemodynamics Interactions In Large-Vessel Occlusion Stroke. Engineering With Computers. 42(4):134. 2026.Ìý

  DOI Link:Ìý

• Laroche, A., Rovito, N., Liu, A., Allaeys, I., Adeoye, O., Heitsch, L., Pizella, S., Bark, D., Di Paola, J., Lee, J.M., Campbell, R., Mukherjee, D., Boilard, E., Denorme, F. Mechanisms Of Von Willebrand Factor Activation Driving No-Reflow In Ischemic Stroke. Proceedings of the National Academy of Sciences. U.S.A. 123(30) e2610397123. 2026.Ìý

  DOI Link:Ìý

• Roopnarinesingh, R., Jani, N.D., Leppert, M., and Mukherjee, D. Understanding Thromboembolus Transport Patterns In The Brain For Stroke In The Presence Of Carotid Artery Stenosis. PLoS Computational Biology. 21(9): e1013269. 2025.Ìý

  DOI Link:Ìý

• Sahni, A., Majee, S., Pal, J.D., McIntyre, E.E., Cao, K., and Mukherjee, D. Hemodynamics Indicates Differences Between Patients With And Without A Stroke Outcome After Left Ventricular Assist Device Implantation. Computers in Biology and Medicine. 189:109877. 2025.Ìý

  DOI Link:Ìý

• Teeraratkul, C., Tomaiuolo, M., Stalker, T.J., and Mukherjee, D. Investigating Clot-flow Interactions By Integrating Intravital Imaging With In Silico Modeling For Analysis Of Flow, Transport, And Hemodynamic Forces. Scientific Reports. 14(1):696. 2024.Ìý

  DOI Link:Ìý

Select Awards

• 2026: National Institutes of Health (NIH) Maximizing Investigators’ Research Award (MIRA)
• 2025: Vogel Leadership Development Fellow, Mechanical Engineering, Â鶹Ãâ·Ñ°æÏÂÔØ
• 2025: Dean’s Excellence Fellowship in Generative AI, Â鶹Ãâ·Ñ°æÏÂÔØ
• 2025: Research and Innovation Office (RIO) Faculty Fellow, Â鶹Ãâ·Ñ°æÏÂÔØ
• 2021: Selected for Pandemic Hyper-accelerator for Science and Technology (PHAST) for pandemic related research and innovation, Venture Partners, Â鶹Ãâ·Ñ°æÏÂÔØ
• 2020: National Institutes of Health (NIH) Trailblazer Award for new and early-stage investigators
• 2020: Oak Ridge Associated Universities (ORAU) Ralph E. Powe Junior Faculty Enhancement Award
• 2019: Â鶹Ãâ·Ñ°æÏÂÔØ Mechanical Engineering Outstanding Graduate Educator Award
• 2018: Insight Health Data Science Fellowship Award
• 2016: Best Poster Award: 5th International Conference on Engineering Frontiers in Pediatric and Congenital Heart Disease
• 2014: Best Poster Award: Society of Petroleum Engineers (SPE) International Oilfield Corrosion Conference and Exhibition
• 2013: Institute Fellow for the Summer Institute for Preparing Future Faculty by the Graduate Division, University of California, Berkeley
• 2011: Outstanding Graduate Student Instructor Award: Graduate Introduction to Finite Element Analysis
• 2010: Best Paper Award: 29th International Conference on Ocean & Offshore, and Arctic Engineering
• 2010: Outreach for Engineers Specialty Forum Scholarship by ASME-IPTI for the International Conference on Ocean & Offshore, and Arctic Engineering
• 2010: Allen D. Wilson Memorial Scholarship by the Department of Mechanical Engineering, University of California, Berkeley